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Your Pen at a Glance

  • Each pen contains: 1000mg of NAD+ (10 doses)
  • Dose: 30 units (100mg) per injection
  • Schedule: Inject once every 3 days
  • Supply: One pen lasts approximately one month

Before You Begin

Please read these instructions carefully before your first injection. If you have any questions, contact your prescribing clinician.

What You'll Need

  • Your Medivive NAD+ Pen (refrigerated)
  • A new needle tip (included in your kit)
  • Alcohol swabs
  • A puncture-resistant container with a lid for needle disposal (e.g., laundry detergent bottle, coffee can)

Storage

  • Keep refrigerated at 2–8°C (35.6–46.4°F)
  • Keep cold while traveling (use a cold pack)
  • Do not freeze
  • Do not use past the expiry date

Where to Inject

This is a subcutaneous injection, meaning it goes into the fat layer just beneath the skin—not into muscle.

Recommended Sites

  • Abdomen: At least 2 inches away from your belly button. Avoid the waistline.
  • Buttock: The outer-upper area where there's more fatty tissue.

Tip: Rotate your injection site each time to avoid irritation. If you injected on the left side of your abdomen last time, try the right side next time.

Injection Steps

  1. Remove the pen cap by pulling it straight off (don't twist). Check that the cartridge is pre-loaded. The solution will typically appear yellow—this is normal (see below).
  2. Attach a new needle tip — peel off the paper tab from the base of the needle, then screw the needle onto the pen. Leave the needle covers on for now.
  3. Clean the injection site with an alcohol swab and let it air dry.
  4. Remove both needle covers — the outer cap and the inner protective cover.
  5. Set the dose to 10–30 units by turning the dial on the pen (as instructed by your provider).
  6. Pinch the skin gently to lift the fat away from the muscle beneath.
  7. Insert the needle into the pinched skin and press the pen down gently to form a slight dimple.
  8. Press the injection button to deliver the dose. A mild sting is normal.
  9. Wait 5 seconds after the dial returns to zero before removing the needle. This ensures the full dose is delivered.
  10. Remove the needle and immediately replace the outer needle cover. Unscrew the needle from the pen and dispose of it in your container.
  11. Replace the pen cap and return the pen to the refrigerator.

What to Expect

Solution Color

The solution in your pen will typically appear yellow. This is completely normal and indicates a high-concentration formula. The yellow color occurs because NAD+ molecules absorb most wavelengths of visible light except yellow. We do not add whitening agents to mask this natural color, as it has no impact on safety or effectiveness.

During Injection

A mild sting during injection is completely normal. This usually fades within a few seconds.

After Injection

Some minor dripping or a small drop of blood at the injection site is normal. You can apply gentle pressure with a clean cotton ball if needed.

Do not share your pen with others. Each pen is for single-patient use only. Always use a new sterile needle for each injection.

Important Notes

If You Miss a Dose

Simply take your next dose when you remember, then continue with your regular schedule (every 3 days). Do not double up to compensate for a missed dose.

Traveling with Your Pen

Use a cold-pack travel case to maintain proper temperature. When flying, keep your pen in your carry-on bag—checked luggage compartments can freeze.

Questions? Contact your prescribing clinician or reach out to us at clyde@medivive.com

Needle Disposal

After each injection, place the used needle in a hard plastic container with a secure lid—such as a laundry detergent bottle or similar household container. When full, tape the lid shut and check with your local pharmacy or waste department for disposal options.

Never throw loose needles in regular household trash.